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Title
Zirconium nitrate: a reusable water tolerant Lewis acid catalyst for the synthesis of N-substituted pyrroles in aqueous media
Type Article
Keywords
Not Record
Abstract
A simple, efficient procedure for the synthesis of 11-(1H-pyrrol-1-yl)-11H-indeno[1,2-b]quinoxaline and 3-(1H-pyrrol-1-yl)indolin-2-one derivatives in aqueous media is described. The condensation reaction between 4-hydroxyproline and isatin derivatives or 11H-indeno[1,2-b]quinoxalin-11-ones, using a catalytic amount of Zr(NO3)4 as a water tolerant Lewis acid catalyst affords, the title compounds in high to excellent yields and in short reaction times.
Researchers Alireza Hasaninejad (First researcher) , Mohammad Reza Mohammadizadeh (Third researcher) ,