10 فروردین 1403
احمد شادي

احمد شادی

مرتبه علمی: استادیار
نشانی: دانشکده علوم و فناوری نانو و زیستی - گروه علوم زیستی
تحصیلات: دکترای تخصصی / زیست شناسی
تلفن: 07731222424
دانشکده: دانشکده علوم و فناوری نانو و زیستی

مشخصات پژوهش

عنوان
یک مرور کلی بر ابزارهای ایمونوانفورماتیک برای پیش بینی اپی توپ: اپی توپ های سلول هایT و B
نوع پژوهش مقالات در همایش ها
کلیدواژه‌ها
epitope prediction, vaccine design, immunoinformatic, bioinformatic, B-cell, T-cell
پژوهشگران مصطفی محمدی (نفر اول) ، محمد جواد صابری (نفر دوم) ، غزل نورآبادی (نفر سوم) ، احمد شادی (نفر چهارم)

چکیده

Today by spreading of existing diseases and emergence of new infections, special attention to the vaccinology is necessary. In the past decade the progress made in the process of gene sequencing, pathogens gene sequencing more rapidly done. That accelerates the process of the new vaccine manufacturing. The protection against invading pathogens and cells infected by viruses aware of the immune system (humoral and cellular immunity) is very important. Aware of this process, it’s necessary in the epitopes prediction process and vaccine design. With respect to the progress made in this field, still tests needed to identify appropriate areas, is costly and requiring inexpensive, practical, fast and with high precision tools is essential. Immunoinformatics was created due to the needs. This science is a branch of bioinformatics, which was formed by bioinformatics fast growing and massive data derived from gene sequencing, immunology and vaccinology. Nowadays many bases as SYFPEITHI, BIMAS, ProPred and NetCTL for T cells and BepiPred, ABCPred, Bcepred for B cells has been created. This article discusses and reviews the available tools to predict the appropriate B and T epitopes for vaccine design.