Efficient thiocyanation of aromatic compounds using NH4SCN, DMSO and H2SO4, By Mohammad Abbasi

Research

Title	Efficient thiocyanation of aromatic compounds using NH4SCN, DMSO and H2SO4
Type	Article
Keywords	Thiocyanation DMSO Indole Phenol Aniline
Journal	TETRAHEDRON LETTERS
DOI	10.1016/j.tetlet.2022.153929
Researchers	Mohammad Abbasi (First researcher) , Najmeh Nowrouzi (Second researcher) , hamed sedaghat (Third researcher)

Abstract

A simple, efficient, and smooth thiocyanation of indoles, phenols and aniline derivatives using NH4SCN, DMSO and H2SO4 in DMF is introduced. Using this procedure, diverse indoles and N-alkyl indoles are selectively thiocyanated at the C-3 position. para-free anilines, N-alkyl anilines and phenols undergo thiocyanation at the para position selectively.