10 فروردین 1403
اسماعيل تماري

اسماعیل تماری

مرتبه علمی: دانشیار
نشانی: دانشکده علوم و فناوری نانو و زیستی - گروه شیمی
تحصیلات: دکترای تخصصی / شیمی تجزیه
تلفن: -
دانشکده: دانشکده علوم و فناوری نانو و زیستی

مشخصات پژوهش

عنوان Electrochemical Oxidation of Desipramine Drug in the Presence of 4,6-Dimethylpyrimidine-2-thiol Nucleophile in Aqueous Acidic Medium
نوع پژوهش مقالات در نشریات
کلیدواژه‌ها
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مجله ELECTROANALYSIS
شناسه DOI
پژوهشگران اسماعیل تماری (نفر اول) ، عزیزاله نژادعلی (نفر دوم) ، شهرام لطفی (نفر سوم)

چکیده

Electrochemical oxidation of desipramine (DES) has been studied in the presence of 4,6-dimethylpyrimidine- 2-thiol (DMPT) as nucleophile in acidic medium by means of cyclic voltammetry, controlled-potential electrolysis and spectroscopic data, as diagnostic techniques. Voltammetric studies of electro-oxidation of desipramine were realized in a range of pH 1.0 to 8.0 in the absence and presence of DMPT. The results indicate the participation of the product of electrochemical oxidation of desipramine in the reaction with DMPT with ECEC electrochemical mechanism. However, the voltammetry and coulometry results imply existence of a catalytic (EC’) electrochemical mechanism in parallel with ECEC electrochemical mechanism. The product has been characterized by IR, 1H NMR, 13C NMR and MS methods.