In the dynamic realm of supramolecular chemistry, supramolecules emerge as complex structures that self-assemble through non-covalent interactions such as hydrogen bonding, ionic interactions, van der Waals forces, and π–π interactions. These assemblies, composed of two or more molecular units, exhibit properties and functions that surpass those of their individual components. Their applications span a wide range—from catalysis and molecular sensing to materials science and biological systems. Their significance lies in the ability to mimic or even exceed the complexity and efficiency of biological systems, enabling the design of molecular structures with high precision and predetermined functionalities. Recent advances in molecular synthesis, host–guest chemistry, and the understanding of intermolecular forces have led to the development of supramolecules with innovative architectures responsive to external stimuli. In the biological domain, supramolecules serve as simplified models for studying complex biological processes, as well as targeted drug delivery systems and molecular imaging agents, highlighting their central role at the interface of chemistry, materials science, and life sciences.
Objective: The synthesis and identification of novel supramolecular complexes of mercury and cobalt metals with pyridine-2,6-dicarboxylic acid and 4-chloro-2,6-diaminopyrimidine ligands.
Methodology: Two novel zero-dimensional supramolecular compounds were synthesized. Compound (1) was obtained via autoclave synthesis using mercury(II) metal and the ligands pyridine-2,6-dicarboxylic acid (HL′) and 4-chloro-2,6-diaminopyrimidine (LCH₃). Compound (2) was synthesized through reflux using cobalt and potassium metals with pyridine-2,6-dicarboxylic acid. This compound features a tetranuclear structure comprising two cobalt and two potassium atoms, coordinated not only with pyridine-2,6-dicarboxylic acid ligands but also with water molecules and chlorine atoms. Furthermore, a cobal