10 فروردین 1403
سالم مرمضي

سالم مرمضی

مرتبه علمی: استادیار
نشانی: دانشکده مهندسی کشاورزی - گروه گیاه پزشکی
تحصیلات: دکترای تخصصی / مهندسی علوم دامی
تلفن: -
دانشکده: دانشکده مهندسی کشاورزی

مشخصات پژوهش

عنوان Cysteamine administration in lambs grazing on mountain pastures: Effects on the body weight, antioxidant capacity, thyroid hormones and growth hormone secretion
نوع پژوهش مقالات در نشریات
کلیدواژه‌ها
CAT, GSH-Px, MDA, SOD, T-AOC
مجله VETERINARY MEDICINE AND SCIENCE
شناسه DOI 10.1002/vms3.644
پژوهشگران برهان شکراللهی (نفر اول) ، عبدالله فضلی (نفر دوم) ، سالم مرمضی (نفر سوم) ، نازیلا سعادتی (نفر چهارم) ، حافظ اشفق احمد (نفر پنجم) ، فیض الحسن (نفر ششم به بعد)

چکیده

This study aimed to evaluate the effects of intravenous injection of cysteamine (CS) on body weight (BW), growth hormone (GH), thyroid hormones (TH) secretion, and antioxidant status of growing lambs grazing on mountain pastures. Fifteen lambs (3–4 months of age) were randomly allocated into three experimental groups which received different dosages of CS: 0, 20, and 50 mg/kg BW−1. The CS was injected on the 1st, 10th, and 20th days of the experiment to the lambs through the jugular vein. Assessment of plasma concentration of GH and TH hormones was carried out at days 0 (a day before the start of CS injections), 15, and 30 of the experiment. The antioxidant enzymes were measured at the end of the experiment. Lambs were weighed at days 0, 10, 20, and 30 of the experiment. The results showed that treatment and time affected the BW, GH, triiodothyronine (T3), and tetraiodothyronine (T4) secretion. The intravenous injection of CS increased the BW of growing lambs (p < 0.01) and increased the plasma concentration of GH, T3, and T4 (p < 0.01). The treatment also enhanced glutathione peroxidase (GSH-Px; p < 0.05) and reduced malondialdehyde concentrations (MDA; p < 0.01). Total antioxidant capacity (T-AOC) level reduced in CS-1 treatment compared to GC and CS-2 treatments (p < 0.01). The levels of superoxide dismutase (SOD) and catalase (CAT) were not affected by CS. In conclusion, intravenous injection of CS improved BW, GH, and TH concentrations and antioxidant capacity in growing lambs grazing on mountain pastures.