Plant-associated medicinal nano-chemistry is an emerging field that combines the principles of nanotechnology with the bioactive compounds derived from plants to develop novel therapeutic agents. This interdisciplinary approach aims to enhance the efficacy, bioavailability, and targeted delivery of phytochemicals, addressing some of the limitations of traditional herbal medicine. The unique role of plant extracts has gained significant importance in the field of nanotechnology due to its environmentally friendly, economically practical, and commercially feasible stimulant activity. The synthesis of stable, uniformly disseminated metallic nanoparticles is an exciting research area of great significance to the biomedical, biopharmaceutical, and biological fields. Plant extract synthesis of nanoparticles is, in general, eco-friendly, cost-effective, non-harmful, a simple process, and a convenient protocol for easy large-scale production. It is therapeutically significant, and most of the phytochemicals inside the plants have the ability to act as capping agents, reducing the metallic ions to their nanoscale size. Nanotechnology involves the manipulation of matter on an atomic, molecular, and supramolecular scale, typically below 100 nanometers. In medicine, it is used to create nanoparticles, nanocarriers, and other nanostructures for drug delivery, imaging, and therapy. Phytochemicals are bioactive compounds found in plants, including alkaloids, flavonoids, terpenoids, phenolics, and others. They possess various therapeutic properties, such as antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. Many phytochemicals have low bioavailability due to poor solubility, stability, or rapid metabolism. Nanotechnology can improve their bioavailability by enhancing solubility, protecting them from degradation, and facilitating controlled release. Nanoparticles can be designed to release phytochemicals in a controlled manner, ensuring a sustained therapeutic
