سالم مرمضی

In the current study, the expression pattern of PRLR gene was investigated during prenatal, milking and drying times in mammary glands of Adani goats having high and low milk breeding values. Samples of Mammary gland tissue taken by biopsy gun and applied to Real Time-PCR gene expression analysis. The statistical model contained fixed effects of breeding value groups, sampling time and interaction between breeding value groups and sampling time, and random effect of animals nested in breeding value groups and interaction between sampling time and animal nested in breeding value. The interaction between breeding value groups and sampling times was significant (p<0.01). In high breeding values group, gene expression abundance in milking time was significantly less than low breeding value group. The results also show that in both groups the maximum of PRLR gene transcription was in drying time. These results indicate that the transcription conditions of PRLR gene in high breeding value group were not stable in different physiological times, therefore it is required to study the conditions and structure of the promoter region of this gene in Adani goats.