Productivity in university is due to variety factors that one from basis factors is mental health. To do divine ceremonies and fasting in the Ninth Lunar Month of Fasting is factors which can perform an effective role in provider of Office Personnel mental health. The present study's purpose is to investigate the efficacy of fasting in the Ninth Lunar Month of Fasting on mental health that do on Office Personnel of Mohaghegh Ardabili. Since in this study use for study one group and not use comparable group and was not selective applying independent variable therefore used quasi-experimental method. Also research design was pretest and posttest for one group. In this study selected with full sampling manner number 206 cases. Results showed that were significant difference in anxiety, depression and body symbols between pretest and posttest. Also there is significant difference in mental health between pretest and posttest. This study indicated that fasting in the Ninth Lunar Month of Fasting can to cause reduction of mental health in university Office Personnel.