Saccharin sulfonic acid (SaSA) is used as a highly efficient and recyclable catalyst
for the one-pot multicomponent condensation of 2-naphthol with arylaldehydes and amides
(thioamides or alkyl carbamates) under green, mild (70 ?C), and solvent-free conditions.
In this reaction, 1-amidoalkyl-2-naphthols, 1-thioamidoalkyl-2-naphthols, 1-carbamatoalkyl-
2-naphthols, bis(1-amidoalkyl-2-naphthol)s, and bis(1-carbamatoalkyl-2-naphthol)s are produced
in high to excellent yields and in relatively short reaction times.