One-Pot, Four-Component Synthesis of Novel Spiro[indeno[2,1-b]quinoxaline-11,4 0 -pyran]-2 0 -amines, By Alireza Hasaninejad

Research

Title	One-Pot, Four-Component Synthesis of Novel Spiro[indeno[2,1-b]quinoxaline-11,4 0 -pyran]-2 0 -amines
Type	Article
Keywords	—
Journal	JOURNAL OF HETEROCYCLIC CHEMISTRY
DOI	—
Researchers	Alireza Hasaninejad (First researcher) , nooshin golzar (Second researcher) ,

Abstract

A one-pot, four-component reaction for the ef?cient synthesis of novel spiro[indeno[2,1-b]quinoxaline-11, -pyran]-2 0 -amines by using InCl is described. The syntheses are achieved by reacting ninhydrin with 1,2diaminobenzenes to give indenoquinoxalines, which are trapped in situ by alkyl malonates and various -methylencarbonyl compounds through cyclization, providing multifunctionalized spiro-substituted indeno ,1-b]quinoxaline-11,4 0 -pyran-2 0 3 -amines.