Onepot, MultiComponent Synthesis of Novel BisSpiro Pyranopyrazole Derivatives in the Presence of DABCO as an Efficient and Reusable Solid Base Catalyst, By Alireza Hasaninejad

Research

Title	Onepot, MultiComponent Synthesis of Novel BisSpiro Pyranopyrazole Derivatives in the Presence of DABCO as an Efficient and Reusable Solid Base Catalyst
Type	Article
Keywords	—
Journal	ChemistrySelect
DOI	—
Researchers	Alireza Hasaninejad (Second researcher)

Abstract

A simple and elegant synthesis of some novel bis?spiro pyranopyrazoles has been achieved via the condensation reaction between bis?isatins, malononitrile, hydrazine hydrate and ??ketoester derivatives in the presence of a catalytic amount of 1, 4?diazabicyclo [2.2.2] octane (DABCO) in ethanol at reflux conditions. The significant features of the present method are structure diversity, product complexity, procedure and work?up simplicity, environmentally friendly, good to excellent yields and catalyst recyclability.