Pyrazole and pyridiopyrimidines derivatives are two important organic compounds which have useful applications in specially of drugs and indicate awide range of biological activities such as antibacterial, antifungal and antitumor. Due to variety of biological and pharmacological properties these compounds are significantly investigated. They are also counted as important synthesis substance in organic synthesis. Therefor,variety of methods are reportedfor synthesis ofdifferent derivatives of pyrazole and uracil.