Replacement of fish meal (FM) with rice protein concentrate (RPC) as a practical diet for the Pacific white shrimp, Litopenaeus vannamei, was evaluated. Five isonitrogenous (36.6% protein) diets, formulated by replacing 0, 25, 50, 75, and 100% of FM by RPC, were fed to shrimp (initial weight of 6.99±0.08 g) five times daily to satiation for 60 days. Relatively high final weight (FW) and weight gain (WG) were obtained in treatments up to 50% of the plant protein inclusion. Above this inclusion level, FW and WG were reduced. Survival was high (? 95%) and similar for all diets. A decreasing trend in apparent digestibility coefficient (excluding dry matter) for crude protein, ether extract, organic matter and gross energy were observed at higher RPC inclusion rates. The results suggest that RPC meal can be a potential candidate for FM replacement up to 50% of the protein in shrimp diets.