Highly Regioselective N-Alkylation of Benzotriazole under Solvent-Free Conditions, By Abdolkarim Zare

Research

Title	Highly Regioselective N-Alkylation of Benzotriazole under Solvent-Free Conditions
Type	Article
Keywords	N-Alkylation, Benzotriazole, Solvent-free, Thermal, Microwave
Journal	Journal of the Iranian Chemical Society
DOI	10.1007/BF03245976
Researchers	A. Khalafi-Nezhad (First researcher) , Abdolkarim Zare (Second researcher) , A. Parhami (Third researcher) , M. N. Soltani Rad (Fourth researcher) , G.R. Nejabat (Fifth researcher)

Abstract

An efficient, simple and solvent-free method for highly regioselective N-alkylation of benzotriazole in the presence of SiO2, K2CO3 and tetrabutylammonium bromide (TBAB) under thermal and microwave conditions has been described. In this method, 1-alkyl benzotriazoles were obtained regioselectively in moderate to high yields and short reaction times.