A Highly Efficient Protocol for the Synthesis of N-Aryl Nucleobases Using Zinc Oxide in Ionic Liquids, By Abdolkarim Zare

Research

Title	A Highly Efficient Protocol for the Synthesis of N-Aryl Nucleobases Using Zinc Oxide in Ionic Liquids
Type	Article
Keywords	N-Aryl nucleobase, Zinc oxide, Ionic liquid, N-Arylation, Microwave
Journal	Journal of the Iranian Chemical Society
DOI	10.1007/BF03246033
Researchers	Abdolkarim Zare (First researcher) , A. Hasaninejad (Second researcher) , A. Khalafi-Nezhad (Third researcher) , A.R. Moosavi Zare (Fourth researcher) , M.H. Beyzavi (Fifth researcher) , F. Khedri (Not in first six researchers) , F. Asadi (Not in first six researchers) , N. Hayati (Not in first six researchers) , A. Asifi (Not in first six researchers)

Abstract

A highly efficient and simple method for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases via Narylation of nucleobases using zinc oxide in 1-butyl-3-methylimidazolium bromide ([bmim]Br) under microwave as well as thermal conditions is described. In both conditions, the title compounds were produced in high to excellent yields and in short reaction times.