Study of an in situ carbocationic system formed from trityl chloride (Ph3CCl) as an efficient organocatalyst for the condensation of dimedone with arylaldehydes, By Abdolkarim Zare

Research

Title	Study of an in situ carbocationic system formed from trityl chloride (Ph3CCl) as an efficient organocatalyst for the condensation of dimedone with arylaldehydes
Type	Article
Keywords	Trityl chloride (Ph3CCl), Trityl carbocation, Organocatalyst, Dimedone (5,5-Dimethyl-1,3-cyclohexanedione), Arylaldehyde, 9-Aryl-1,8-dioxo-octahydroxanthene
Journal	Iranian Journal of Catalysis
DOI	https://oiccpress.com/ijc/article/view/3759
Researchers	Abdolkarim Zare (First researcher) , Maria Merajoddin (Second researcher) , Mohammad Ali Zolfigol (Third researcher)

Abstract

Organocatalyst trityl chloride (Ph3CCl), by in situ formation of trityl carbocation with inherent instability, efficiently catalyzes the condensation of dimedone (5,5-dimethyl-1,3-cyclohexanedione) (2 equiv.) with arylaldehydes (1 equiv.) under solvent-free conditions to afford 9-aryl-1,8-dioxo-octahydroxanthenes in high to excellent yields and in relatively short reaction times. Formation of the carbocationic system is confirmed by studying IR, 1H NMR and UV spectra according to the literature. Moreover, a plausible mechanism based on the literature and observations is proposed for the reaction.