In situ generation of trityl carbocation (Ph3C+) as a homogeneous organocatalyst for the efficient synthesis of 4,4

Research

Title	In situ generation of trityl carbocation (Ph3C+) as a homogeneous organocatalyst for the efficient synthesis of 4,4'‐(arylmethylene)‐bis(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐ol)s
Type	Article
Keywords	Trityl chloride (Ph3CCl); Trityl carbocation (Ph3C+); 4,4'‐(Arylmethylene)‐bis(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐ol); 3‐Methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one; Solvent‐free synthesis
Journal	CHINESE JOURNAL OF CATALYSIS
DOI	10.1016/S1872-2067(12)60728-1
Researchers	Abdolkarim Zare (First researcher) , Maria Merajoddin (Second researcher) , Ahmad Reza Moosavi-Zare (Third researcher) , Mahmoud Zarei (Fourth researcher)

Abstract

Trityl chloride (Ph3CCl) efficiently catalyzes the condensation of 3‐methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one and aromatic aldehydes under mild and solvent‐free conditions, affording 4,4'‐ (arylmethylene)‐bis(3‐methyl‐1‐phenyl‐1H‐ pyrazol‐5‐ol)s in high to excellent yields and in short reaction time. The presence of the requisite organocatalytic trityl carbocation (Ph3C+) species was confirmed by analysis of infred, 1H NMR, and ultra violet spectral data. A plausible mechanism was proposed for the reaction based on the observations and literature precedent.

Abdolkarim Zare

Research

Abstract