January 24, 2025
Abdolkarim Zare

Abdolkarim Zare

Academic Rank: Professor
Address: Department of Chemistry, Faculty of Nano and Bio Science and Technology
Degree: Ph.D in Organic chemistry
Phone: 07731222717
Faculty: Faculty of Nano and Biotechnology

Research

Title Preparation, characterization and application of nano-[Fe3O4@- SiO2@R-NHMe2][H2PO4] as a novel magnetically recoverable catalyst for the synthesis of pyrimido[4,5-b]quinolines
Type Article
Keywords
Organic-inorganic hybrid magnetic nanomaterial; Nano-[Fe3O4@-SiO2@R-NHMe2][H2PO4] (nano-[FSRN][H2PO4]); Pyrimido[4,5-b]quinolone; 6-Amino-1,3-dimethyluracil; Multi-component reaction Solvent-free
Journal JOURNAL OF MOLECULAR STRUCTURE
DOI 10.1016/j.molstruc.2020.128030
Researchers Abdolkarim Zare (First researcher) , Nesa Lotfifar (Second researcher) , Manije Dianat (Third researcher)

Abstract

A novel organic-inorganic hybrid magnetic nanomaterial namely nano-[Fe3O4@-SiO2@R-NHMe2][H2PO4] (nano-[FSRN][H2PO4]) has been prepared, and characterized by FT-IR, EDS, FE-SEM, VSM, XRD and TGA analyses. Afterward, an important class of uracil-bearing heterocycles namely pyrimido[4,5-b]quinolines has been synthesized through the one-pot multi-component reaction of 6-amino-1,3-dimethyluracil with arylaldehydes and dimedone using nano-[FSRN][H2PO4] as a dual-functional catalyst under solvent-free conditions. High yields, short reaction times, magnetic recoverability of the catalyst, no need to column chromatography for purification of the products and good compliance with green chemistry protocols are some advantages of the work.