Effective and Rapid Synthesis of Pyrido[2,3-d:6,5-d′]Dipyrimidines Catalyzed by a Mesoporous Recoverable Silica-Based Nanomaterial, By Abdolkarim Zare

Research

Title	Effective and Rapid Synthesis of Pyrido[2,3-d:6,5-d′]Dipyrimidines Catalyzed by a Mesoporous Recoverable Silica-Based Nanomaterial
Type	Article
Keywords	Pyrido[2,3-d:6,5-d′]dipyrimidines; Nano-[SiO2-R-NMe2SO3H][Cl]; Mesoporous nanocatalyst; Multi-component reaction; Solvent-free
Journal	Silicon
DOI	10.1007/s12633-019-00235-0
Researchers	Alireza Kohzadian (First researcher) , Abdolkarim Zare (Second researcher)

Abstract

A simple, rapid and effective protocol for the synthesis pyrido[2,3-d:6,5-d′]dipyrimidines has been developed via the one-pot multi-component reaction of arylaldehydes, 2-thiobarbituric acid and NH4OAc using nano-[SiO2-R-NMe2SO3H][Cl] as a mesoporous nanaocatalyst in solvent-free conditions. The remarkable features of this protocol include superiority relative to the reported methods in terms of two or more of these items: the reaction times, yields, the reaction temperature and conditions.