Efficient method for the direct preparation of aryl carboxylates from carboxylic acids using tosyl chloride under solvent-free conditions, By Abdolkarim Zare

Research

Title	Efficient method for the direct preparation of aryl carboxylates from carboxylic acids using tosyl chloride under solvent-free conditions
Type	Article
Keywords	Aryl carboxylate, Carboxylic acid, Tosyl chloride, Solvent-free, 1-Methylimidazole
Journal	Journal of the Iranian Chemical Society
DOI	10.1007/BF03245996
Researchers	A. Khalafi-Nezhad (First researcher) , A. Parhami (Second researcher) , Abdolkarim Zare (Third researcher) , A.R. Moosavi Zare (Fourth researcher)

Abstract

A simple, clean and efficient solvent-free procedure for the preparation of aryl carboxylates is described from the direct reaction of carboxylic acids and phenols, in the presence of 1-methylimidazole as base and tosyl chloride (TsCl) as coupling agent. This method can be easily applied for different substituted phenols and carboxylic acids. It can also be applied for the selective acylation when other functional group such as hydroxyl is present on phenol ring.