KF/Al2O3 as a highly efficient reagent for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases, By Abdolkarim Zare

Research

Title	KF/Al2O3 as a highly efficient reagent for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases
Type	Article
Keywords	KF/Al2O3, N-aryl nucleobase, pyrimidine, purine, N-arylation, microwave
Journal	ARKIVOC
DOI	10.3998/ark.5550190.0009.g17
Researchers	Abdolkarim Zare (First researcher) , Alireza Hasaninejad (Second researcher) , Ahmad Reza Moosavi-Zare (Third researcher) , Mohammad Hassan Beyzavi (Fourth researcher) , Ali Khalafi-Nezhad (Fifth researcher) , Nasrin Pishahang (Not in first six researchers) , Zahra Parsaee (Not in first six researchers) , Parvin Mahdavinasab (Not in first six researchers) , Nahid Hayati (Not in first six researchers)

Abstract

KF/Al2O3 acts as a highly efficient reagent for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases as biologically interesting compounds via N-arylation reaction under microwave as well as conventional heating conditions. Using this method, the title compounds are produced in good to excellent yields and relatively short reaction times.