KF/Al2O3 as a Highly Efficient, Green, Heterogeneous, and Reusable Catalytic System for the Solvent-Free Synthesis of Carboacyclic Nucleosides via Michael Addition Reaction, By Abdolkarim Zare

Research

Title	KF/Al2O3 as a Highly Efficient, Green, Heterogeneous, and Reusable Catalytic System for the Solvent-Free Synthesis of Carboacyclic Nucleosides via Michael Addition Reaction
Type	Article
Keywords	Carboacyclic nucleoside, KF/Al2O3, Michael addition, microwave, nucleobase, solvent-free
Journal	SYNTHETIC COMMUNICATIONS
DOI	10.1080/00397910802369711
Researchers	Abdolkarim Zare (First researcher) , Alireza Hasaninejad (Second researcher) , Mohammad Hassan Beyzavi (Third researcher) , Ahmad Reza Moosavi-Zare (Fourth researcher) , Ali Khalafi-Nezhad (Fifth researcher) , Fatemeh Asadi (Not in first six researchers) , Leila Baramaki (Not in first six researchers) , Sedigheh Jomhori-Angali (Not in first six researchers) , Rokhsareh Ghaleh-Golabi (Not in first six researchers)

Abstract

KF/Al2O3 acts as an efficient catalytic system for the synthesis of carboacyclic nucleosides via Michael addition of pyrimidine and purine nucleobases to α,β-unsaturated esters under solvent-free and microwave conditions. Using this method, the title compounds are produced in good to excellent yields and short reaction times.