PEG-SO3H as a new, highly efficient and homogeneous polymeric catalyst for the synthesis of bis(indolyl)methanes and 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1Hpyrazol-5-ol)s in water, By Abdolkarim Zare

Research

Title	PEG-SO3H as a new, highly efficient and homogeneous polymeric catalyst for the synthesis of bis(indolyl)methanes and 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1Hpyrazol-5-ol)s in water
Type	Article
Keywords	Poly(ethylene glycol)-bound sulfonic acid (PEG-SO3H), Bis(indolyl)methane, Bis(pyrazolyl)methane, 4,4´-(Arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol), Polymeric catalyst
Journal	Journal of the Iranian Chemical Society
DOI	10.1007/BF03249075
Researchers	A. Hasaninejad (First researcher) , Mohsen Shekouhy (Second researcher) , Abdolkarim Zare (Third researcher) , S.M.S. Hoseini Ghattali (Fourth researcher) , Nooshin Golzar (Fifth researcher)

Abstract

In this work, a green, simple and highly efficient procedure for the synthesis of bis(indolyl)methanes and 4,4′- (arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s [as an important class of bis(pyrazolyl)methanes] is described. The condensation of indoles or 1-phenyl-3-methylpyrazol-5-one with carbonyl compounds catalyzed by poly(ethylene glycol)-bound sulfonic acid (PEG-SO3H) in water affords the title compounds in high yields and relatively short reaction times.