Synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles using disulfonic acid imidazolium chloroaluminate as a dual and heterogeneous catalyst, By Abdolkarim Zare

Research

Title	Synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles using disulfonic acid imidazolium chloroaluminate as a dual and heterogeneous catalyst
Type	Article
Keywords	6-Amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles; disulfonic acid imidazolium chloroaluminate; dual and heterogeneous catalyst; multi-component condensation
Journal	NEW JOURNAL OF CHEMISTRY
DOI	10.1039/C3NJ00629H
Researchers	Ahmad Reza Moosavi-Zare (First researcher) , Mohammad Ali Zolfigol (Second researcher) , Ehsan Noroozizadeh (Third researcher) , Mahsa Tavasoli (Fourth researcher) , Vahid Khakyzadeh (Fifth researcher) , Abdolkarim Zare (Not in first six researchers)

Abstract

In this work, disulfonic acid imidazolium chloroaluminate {[Dsim]AlCl4} is applied as a new acidic and heterogeneous catalyst for green, simple and efficient synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles by the one-pot multi-component condensation of aryl aldehydes with ethyl acetoacetate, malononitrile and hydrazine hydrate at 80 °C under solvent-free conditions.