One-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles using sulfonic acid-functionalized pyridinium chloride as an efficient and recyclable catalyst, By Abdolkarim Zare

Research

Title	One-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles using sulfonic acid-functionalized pyridinium chloride as an efficient and recyclable catalyst
Type	Article
Keywords	1,2,4,5-tetrasubstituted imidazole; Sulfonic acidfunctionalized pyridinium chloride; Ionic liquid; Solvent-free; Benzyl; Primary amine; Aldehyde
Journal	Scientia Iranica
DOI	https://scientiairanica.sharif.edu/article_3775.ht
Researchers	A.R. Moosavi Zare (First researcher) , Zhila Asgari (Second researcher) , Abdolkarim Zare (Third researcher) , Mohammad Ali Zolfigol (Fourth researcher)

Abstract

Sulfonic acid-functionalized pyridinium chloride ionic liquid {[Pyridine–SO3H]Cl} can effectively promote the one-pot multi-component condensation reaction between benzil, aldehydes, primary amines and ammonium acetate under solvent-free conditions at 100 ºC to give the desired 1,2,4,5-tetrasubstituted imidazoles, in high yields and short reaction times.