Triethylaminium-N-sulfonic Acid Tetrachloroaluminate (TSAT) as a New Ionic Liquid Catalyst for the Synthesis of [1,2,4]Triazolo[1,5-a]pyrimidines, By Abdolkarim Zare

Research

Title	Triethylaminium-N-sulfonic Acid Tetrachloroaluminate (TSAT) as a New Ionic Liquid Catalyst for the Synthesis of [1,2,4]Triazolo[1,5-a]pyrimidines
Type	Article
Keywords	Triethylaminium-N-sulfonic acid tetrachloroaluminate (TSAT); [1,4]Triazolo[1,5-a] pyrimidines-6-carboxamide; Acetoacetanilide; 3-Amino-1,2,4-triazole
Journal	Organic Chemistry Research
DOI	10.22036/org.chem.2018.133755.1151
Researchers	Asieh Kargar-Dolatabadi (First researcher) , Seyed Sajad Sajadikhah (Second researcher) , Abdolkarim Zare (Third researcher)

Abstract

Triethylaminium-N-sulfonic acid tetrachloroaluminate (TSAT) as a new ionic liquid was synthesized and characterized by its FT-IR, 1H, 13C NMR and mass spectra as well as TG and DTG diagrams. This ionic liquid was employed as a catalyst for the synthesis of [1,2,4]triazolo[1,5-a]pyrimidines-6-carboxamides via one-pot three-component reaction of aromatic aldehydes, acetoacetanilide and 3-amino-1,2,4-triazole under solvent-free conditions at 60 °C .The salient features of the present protocol are mild reaction condition, easy isolation of products and clean reaction profiles.