Regioselective N‐Arylation of Some Pyrimidine and Purine Nucleobases, By Abdolkarim Zare

Research

Title	Regioselective N‐Arylation of Some Pyrimidine and Purine Nucleobases
Type	Article
Keywords	N-arylation, nucleobase, purine, pyrimidine
Journal	SYNTHETIC COMMUNICATIONS
DOI	10.1080/00397910600943535
Researchers	A. Khalafi-Nezhad (First researcher) , Abdolkarim Zare (Second researcher) , Abolfath Parhami (Third researcher) , Mohammad Navid Soltani Rad (Fourth researcher) , Gholam Reza Nejabat (Fifth researcher)

Abstract

N‐Arylation of some pyrimidine and purine nucleobases in the presence of SiO2 and Cs2CO3 under solvent‐free as well as in solution conditions is described. In these conditions, N1‐aryl pyrimidines and N9‐aryl purines have been obtained regioselectively in moderate to high yields with relatively short reaction times.