داریوش صابری

In this thesis, the reaction in the deep eutectic solvents are discussed; For this purpose, three reactions including: the formation of the derivatives of N-acyl urea in choline chloride and urea deep eutectic solvents, addition copper oxide catalyst immobilized on maghemite a synthesis of some derivatives of thioamide in potassium carbonate and glycerol deep eutectic solvent (Gly-K2CO3) and finally the synthesis reaction of derivatives of N, N-dicyclohexyl guanidine in the presence of copper oxide catalyst fixed on maghemite, were evaluated. But in the case of the reaction of Willgerodt, it seems the presence of sulfur makes a poisoned catalyst surface and prevents the return of it to the catalytic cycle, so this reaction is done well in deep eutectic solvent with good yield without the presence of a metal-based nanoparticles. In the case of the amination with DCC in order to synthesize guanidine derivatives in deep eutectic solvent, it did not have good results which can be assumed this result should be due to the non-activation of the reactants or the catalyst in this environment. The products of this reaction analyzed with Infra-Red spectroscopy (FT-IR) and Nuclear Magnetic Resonance of Hydrogen (1HNMR). Obviously, the results obtained by the successful synthesis are in accordance with data of reference compounds.