Background: Electrochemistry is a very good way to study the mechanism of
chemical reactions and to determine the sequence of chemical and electrochemical
reactions. A large part of this field is the study of chemicals and chemical changes
caused by the passage of electric current and the production of electrical energy by
chemical reactions, which means the measurement of electrical quantity such as
current, Potential or charge and their relationship to chemical parameters.
Aim: Due to the fact that not much research has been done on the electrochemical
oxidation mechanism of Febantel, in this study the mechanism of electrochemical
oxidation of Febantel and the relative simulation of its metabolism in animals using
cyclic voltammetry are studied.
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Methodology: In this thesis Electrochemical oxidation of Febantel in the presence
and absence of sodium benzenesulfinicacid in acetonitrile and tetra butylammonium-perchlorate solution using cyclic voltammetry on the surface of glassy
carbon electrode and coulometry in a double-walled cell containing Three graphite
electrodes and an Ag / AgCl reference electrode and a platinum auxiliary electrode
were performed at constant potential.
Conclusions: The results of the cyclic voltammogram analysis showed that the first
electrochemical oxidation of Febantel was of the quasi-reversible type, during
which two electrons and two protons were transferred. And the second oxidation of
the febantel is of the irreversible type, during which two electrons are transferred
and has an EE mechanism. Further study of febantel cycle cyclic voltammograms
in the presence and absence of sodium, benzene, sulfonic acid showed that the
oxidized form of febantel participated in an adverse reaction of type 1 and 4 by
Michael and reacted with nucleophiles. Vick follows the electrochemical
mechanism of ECE.