14 آذر 1403
فرشته بيات شاه پرست

فرشته بیات شاه پرست

مرتبه علمی: استادیار
نشانی: دانشکده مهندسی کشاورزی - گروه مهندسی تولید و ژنتیک گیاهی
تحصیلات: دکترای تخصصی / اصلاح نباتات
تلفن: 07733445182
دانشکده: دانشکده مهندسی کشاورزی

مشخصات پژوهش

عنوان Algal Cells-Derived Extracellular Vesicles: A Review With Special Emphasis on Their Antimicrobial Effects
نوع پژوهش مقالات در نشریات
کلیدواژه‌ها
exosome, algae, stem cell, antimicrobial, marine
مجله Frontiers in Microbiology
شناسه DOI 3389/fmicb.2021.785716
پژوهشگران فرشته بیات شاه پرست (نفر اول) ، علیرضا افشار (نفر دوم) ، ندا باغبان (نفر سوم)

چکیده

Extracellular vesicles (EVs) originated from different cells of approximately all kinds of organisms, recently got more attention because of their potential in the treatment of diseases and reconstructive medicine. To date, lots of studies have been performed on mammalian-derived vesicles, but little attention has been paid to algae and marine cells as valuable sources of EVs. Proving the promising role of EVs in medicine requires sufficient resources to produce qualified microvesicles. Algae, same as its other sister groups, such as plants, have stem cells and stem cell niches. Previous studies showed the EVs in plants and marine cells. So, this study was set out to talk about algal extracellular vesicles. EVs play a major role in cell-to-cell communication to convey molecules, such as RNA/DNA, metabolites, proteins, and lipids within. The components of EVs depends on the origin of the primitive cells or tissues and the isolation method. Sufficient resources are needed to produce high-quality, stable, and compatible EVs as a drug or drug delivery system. Plant stem cells have great potential as a new controllable resource for the production of EVs. The EVs secreted from stem cells can easily be extracted from the cell culture medium and evaluated for medicinal uses. In this review, the aim is to introduce algae stem cells as well as EVs derived from algal cells. In the following, the production of the EVs¸ the properties of EVs extracted from these sources and their antimicrobial effects will be discussed.