Nowadays, breast cancer is one of the leading causes of women’s death in
the world. If breast cancer is detected at the initial stages, it can ensure
long-term survival. Numerous methods have been proposed for the early
prediction of such cancer. However, efforts are still ongoing, given the
importance of the problem. Artificial Neural Networks (ANN) are
a prevalent machine learning algorithm, which is very popular for prediction and classification problems. In this paper, an Intelligent Ensemble
Classification method based on Multi-Layer Perceptron neural network
(IEC-MLP) is proposed for breast cancer diagnosis. The proposed method
consists of two stages: parameters optimisation and ensemble classification. In the first stage, the MLP Neural Network (MLP-NN) parameters,
including optimal features, hidden layers, hidden nodes and weights, are
optimised with the help of an Evolutionary Algorithm (EA), aiming at
maximising the classification accuracy. In the second stage, an ensemble
classification algorithm of MLP-NN with optimised parameters is applied
to classify the patients. Our proposed IEC-MLP method not only reduces
the complexity of MLP-NN and effectively selects the optimal subset of
features but also minimises the misclassification cost. The classification
results have been evaluated using the IEC-MLP over different breast
cancer datasets, and the prediction results have been auspicious
(98.74% accuracy on the WBCD dataset). It is noteworthy that the proposed method outperforms the GAANN and CAFS algorithms and other
state-of-the-art classifiers. In addition, IEC-MLP is also capable of being
employed in diagnosing other cancer types.