One of the critical periods in the socio - economic life of the Persian Gulf was the last years of Reza Shah Reign and the beginning of MohammadReza Shah Reign. The synchronization of the drought due to World War II and the occupation of Iran by the Allied forces led to the above phenomenon have influenced various economic and social aspects of coastal communities and the northern coasts of Persian Gulf in an unprecedented manner. The main question of this study is to investigate and explain the economic and social consequences of famine in the northern ports of Persian Gulf between 1938 and 1945. This research, which has been written in historical analysis by using library sources, archival documents, publications and oral history, seeks to investigate and explain the above consequences. The results of this study indicated that there is a severe shortage of food and significant deaths on coastal banks and along the northern coast of the Persian Gulf between the 8th province (Hormozgan) to areas of 7th province, Larestan and Booshehr. Also, this event leads to the spread of insecurity in those regions. The continuation of the drought and famine caused to migrate the residents to the 6th province (Khuzestan) to escape the crisis. This event relied on the extensive activity of the oil industry in Khuzestan and the hope of earning money there.