An efficient strategy for the synthesis of benzamides from acetamides and aryl
iodides using 1 mol% Pd (OAc)2 as catalyst and Cr (CO)6 as CO?precursor is
described. This new synthetic methodology displays high functional group tolerance
on both substrates and avoids the need for ligands, reducing agents, or
other additives. The corresponding products were obtained in good to excellent
yields at atmospheric pressure under mild reaction conditions.