محمد عباسی

A new efficient, one-pot method to get thiobenzamide compounds from benzyl halides, amines, and Na2S2O3 is reported. A benzylic halide is treated with Na2S2O3 in DMSO until the halide is completely consumed. Next, the reaction is continued by adding a primary or secondary amine to the reaction mixture to synthesize thiobenzamides simply. This procedure does not require a special catalyst or any additive to afford thiobenzamides in good to excellent yields.