Oxidative coupling of dibenzyl disulfide with amines catalyzed by quinoline‑bromine complex: access to thioamides, By Mohammad Abbasi

Research

Title	Oxidative coupling of dibenzyl disulfide with amines catalyzed by quinoline‑bromine complex: access to thioamides
Type	Article
Keywords	Thioamide · Bromine sources · Disulfide · Metal-free · Quinoline-bromine complex
Journal	MOLECULAR DIVERSITY
DOI	10.1007/s11030-022-10403-x
Researchers	Mohammad Abbasi (Second researcher)

Abstract

Abstract The reaction of dibenzyl disulfide with various bromine complexes as oxidants and DMSO as solvent can produce thioamides in high yield at 110 °C. Tertiary amines like pyridine and quinoline, which were utilized in this catalyst, are known to generate bromine-addition complexes. The approach is metal- and additive-free, making it a simple and cost-effective way to make a variety of thioamides under favorable circumstances.