Mohsen Mehrabi

There are various treatment methods to treat cancer as a difficult disease. The most common of these methods are chemotherapy, surgery and radiation therapy. But it is worth noting that these treatment methods have many side effects, so it is very important to find a minimally invasive treatment method with high treatment efficiency. Photothermal therapy is one of the appropriate treatment methods due to precise targeting of cancer, low invasiveness and new mechanisms of action. In addition to photothermal therapy, cancer treatments can be combined to increase treatment efficiency.For example, photothermal therapy is combined with chemotherapy, and the therapeutic agent in this combination includes a photothermal therapeutic agent that converts the light received from the laser into heat, and a drug carrier in which the chemotherapy drug is loaded, and photothermal therapy and Chemotherapy is applied at the same time. To investigate the effect of photothermal therapy of graphene quantum dots-mesoporous silica nanoparticles-copper sulfide nanoparticles as a nanocomposite and to investigate the chemotherapy effect of doxorubicin drug loaded in nanocomposite. In this research, copper sulfide nanoparticles were used along with graphene quantum dots as a photothermal therapy agent, and mesoporous silica nanoparticles were used as doxorubicin drug carriers. After making the nanocomposite, 2 ml of it as a solution was exposed to 808 nm laser radiation with a power of 1000 mW, and the effects of photothermal therapy were observed and recorded with a temperature sensor. To check the effect of chemotherapy, the optimal amount of drug was loaded into the nanocomposite and then its accuracy was measured by ultraviolet-visible spectroscopy. The results obtained from the research are as follows: Photothermal therapy effect of nanocomposite graphene quantum dots-mesoporous silica nanoparticles-copper sulfide nanoparticles was obtained at 21.5 degrees Celsius. The capacity of doxor