Mohsen Mehrabi

Photothermal therapy is a safe and non-invasive method for cancer treatment in the last few decades. In this method, cancer cells are exposed to infrared rays with a specific wavelength and time. To convert light into heat, silver and copper nanoparticles are used to increase the temperature and increase the surface plasmon, which is a promising treatment for benign and malignant tumors. Photothermal therapy is a method with minimal side effects, easy, low toxicity, the possibility of precise targeting, low cost and available to the whole public which has been noticed by many researchers. In this method, two parameters are very important: 1- The production of a light-absorbing material with a low cost and an easy and accessible method. 2- This material must have a wavelength that can penetrate deeply and not harm the surrounding tissues. Research on the nanocomposite of semi-porous silica nanoparticles, graphene quantum dots contaminated with silver and copper impurity, in which the chemotherapy drug doxorubicin is loaded in its pores, was analyzed and investigated in the photothermal therapy process. The method of making MSNs is the CTAB template method and the method of making graphene quantum dots is the hydrothermal method and the addition of impurities to the graphene quantum dots is the doped and decorated method. These methods are easy, available, and do not require expensive equipment. In this research, semi-porous silica nanoparticles are used as drug carriers, graphene quantum dots as photothermal therapy agents, silver and copper impurities as light absorbers and temperature enhancers. Finally, 808 nm laser radiation with a power of 1 watt is used to check the photothermal therapy effect. To analyze and investigate the structural properties and characteristics of nanoparticles and compounds produced by transmission electron microscope, X-ray diffraction, scanning electron microscope, porosity and specific surface area of solids, and X-ray energy diffracti