Mohammad Mohammadi

Recent advancements in nuclear physics and simulation tools have significantly enhanced our understanding of the effects of radiation in therapy, enabling accurate estimates of the energy absorbed by tissues and the doses delivered to tumors and adjacent organs. This thesis investigates radiotherapy for gastric cancer tumors using the Geant4 Monte Carlo simulation tool along with publicly available codes. By integrating the human phantom computational code (referenced as ICRP110) with the Katana irradiation device (Hadron Therapy) , we create a comprehensive simulation framework. We modeled the gastric tumor as a cylinder and irradiated it with both proton and carbon-12 ion beams. The results yield important data on the dose delivered at the end of the path (Spread-Out Bragg Peak) and the doses received by organs at risk (OAR). This research not only advances the understanding of cancer treatment but also paves the way for more targeted and effective therapies, ultimately enhancing patient outcomes in the fight against gastric cancer.