One of the methods to strengthen the structures against the seismic lateral loading is the employment of the composite columns. A concrete-filled tube (CFT) has the cumulative advantages of steel and concrete. Concrete-filled steel tube columns have been widely used in the moment-resisting frame (MRF) structures, located in both non-seismic zones and high-risk seismic zones. In this paper, the results of studies on two important seismic parameters of ductility and the response modification factor (RMF) of the MRFs with CFT columns are submitted. While the studies are carried out, the effects of span length-story height ratio, the strength of materials and seismic behavior of MRFs are considered. In this regard, the ductility, RMF and the strength of 36 models of the steel MRFs with CFTs are analyzed. The fiber plastic hinges numerical simulation and pushover analysis method are used in the calculations. Based on the obtained results, the RMFs suitable for the 5-, 10- and 15- story frames are proposed.