نجمه نوروزی

A one-pot efficient synthesis of b-aryl-b-sulfanyl ketones is introduced via a tandem aldol condensationthia- Michael addition process using NaOH in the poly ethylene glycol (PEG-200). Addition of different thiols in situ generated from the reaction of alkyl halides with thiourea to chalcones, formed in situ from the condensation of acetophenone derivatives with benzaldehydes, led to a high yielding synthesis of the products.