Najmeh Nowrouzi

In the first part of this thesis, new cyclophane derivatives are synthesized from the reaction of γ-substituted vinamidinium salts with 1,4-Phenylenedimethanamine and 2,3,5,6-tetramethylbenzene-1,4-diamine in the presence of acetic acid and acetonitrile as solvent. In another part of this study, copper iodide has been used as catalyst for developing a new route to 3-sulfenylindoles from the reaction of aryl halides with indole derivatives in the presence of thiourea and hexachloroethane in DMSO at 120 oC in less than an hour. This catalytic system is also used for oxidative coupling of active methylen compounds with benzenthiols. Benzenthiols are in situ generated in the reaction mixture from aryl halides and thiourea as sulfur transfer reagent. α-Thioaryl compounds are obtained in excellent yields and in short reaction times via the process which is free from the foul smell of thiols.