A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts†, By Najmeh Nowrouzi

Research

Title	A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts†
Type	Article
Keywords	cyclophanes, vinamidinium salts
Journal	RSC Advances
DOI	10.1039/d0ra10548a
Researchers	nooshin golzar (First researcher) , Abdolmohammad Mehranpour (Second researcher) , Najmeh Nowrouzi (Third researcher)

Abstract

In this study, an efficient method for the synthesis of new cyclophanes (5a–f, 6a–g) through the condensation of 1,4-phenylenedimethanamine (3) or 2,3,5,6-tetramethylbenzene-1,4-diamine (4) with 2- substituted vinamidiniums (2a–g) is described. The cyclophane derivatives are obtained in good to excellent yields in the presence of acetic acid in refluxing acetonitrile after 15 h. The structure of new compounds was validated based on their spectral data (1H NMR, 13C NMR, IR) and elemental analysis.