CuI-catalyzed thioarylation of active methylene compounds with in situ generated benzenethiols: Preparation of a-thioaryl-b-dicarbonyls and 4-thioaryl-5-pyrazolones, By Najmeh Nowrouzi

Research

Title	CuI-catalyzed thioarylation of active methylene compounds with in situ generated benzenethiols: Preparation of a-thioaryl-b-dicarbonyls and 4-thioaryl-5-pyrazolones
Type	Article
Keywords	—
Journal	TETRAHEDRON
DOI	—
Researchers	nooshin golzar (First researcher) , Najmeh Nowrouzi (Second researcher) , Mohammad Abbasi (Third researcher)

Abstract

In this paper, a one-step copper-catalyzed procedure for oxidative coupling of active methylene compounds including cyclic b-diketones, cyclic b-ketoesters and 5-pyrazolone with benzenethiols is described. Benzenethiols are in situ generated in the reaction mixture from aryl halides and thiourea as sulfur transfer reagent. a-Thioaryl compounds are obtained in excellent yields and in short reaction time via the process which is free from the foul smell of thiols.