December 22, 2024
Najmeh Nowrouzi

Najmeh Nowrouzi

Academic Rank: Professor
Address:
Degree: Ph.D in شیمی آلی
Phone: -
Faculty: Faculty of Nano and Biotechnology

Research

Title
The use of N-heterocyclic carbon as an organic catalyst in the synthesis of imidazoles, pyrroles and disulfides.
Type Thesis
Keywords
كارين، ايميدازول، پيرول، دي سولفيد، كاتاليزور آلي
Researchers Najmeh Nowrouzi (Primary advisor) , Dariush Saberi (Advisor)

Abstract

Background: One of the most important developments in the chemistry of homogeneous organic catalysts and organometallic catalysts in recent decades has been the use of stable N-heterocyclic carbenes. The study of the chemistry of nucleophilic carbenes started in 1960 and after the isolation of the first stable carbene and its analysis by Argendo, the use of N-heterocyclic carbenes in organic chemistry increased widely, so that in the last two decades, they have found wide applications in organic chemistry. N-heterocyclic carbenes from the reaction between A base and an alide salt with a heterocycle ring are obtained, and by combining B with high selectivity and reactivity, they turn simple substrates into complex molecules. Heterocycle compounds such as imidazoles and pyrroles and disulfide compounds due to their importance in the fields of They are of special importance in various sciences and many methods have been reported for their synthesis. Nowadays, the use of tandem (consecutive) monolayer reactions is of interest because it does not require stepwise separation of intermediates. In this research, it has been tried to use N-heterocycle carbenesynthesis of various compounds during tandem reactions.