April 30, 2025
Sedigheh Hashemnia

Sedigheh Hashemnia

Academic Rank: Associate professor
Address: Department of Chemistry, Faculty of Nano and Bioscience and Technology, Persian Gulf University, Bushehr 75169, Iran
Degree: Ph.D in Biochemistry
Phone: 07733441494
Faculty: Faculty of Nano and Biotechnology

Research

Title
Fucoxanthin extraction from Sargassum brown algae (Persian Gulf coastal zone) with deep eutectic solvents choline chloride: ethylene glycol and choline chloride: lactic acid and investigation of its antioxidant properties.
Type Thesis
Keywords
حلال فرازودگداز، فوكوزانتين، جلبك قهوه اي سارگاسوم، خليج فارس، اثر آنتي اكسيداني
Researchers Zohre Azizi (Student) , Dariush Saberi (Primary advisor) , Sedigheh Hashemnia (Primary advisor) , Dara Bagheri (Advisor)

Abstract

Background: Fucoxanthin, one of the most prominent carotenoids, is renowned for its extraordinary biological properties. Predominantly extracted from brown algae and certain microalgae, this compound has garnered significant attention in the pharmaceutical, food, and cosmetic industries due to its antioxidant, anti-inflammatory, and anti-cancer properties. Fucoxanthin is also noted for its ability to reduce blood lipid levels and regulate blood pressure, making it a promising agent for the prevention of cardiovascular diseases. Traditional methods of fucoxanthin extraction using conventional solvents often face challenges related to environmental sustainability and efficiency. As a result, the use of deep eutectic solvents (DESs), which are both eco-friendly and more efficient, has emerged as a viable alternative, addressing these concerns while providing enhanced extraction performance. Aim: The aim of this study is to investigate the potential for fucoxanthin extraction from brown algae Sargassum using deep eutectic solvents (DESs), which are more environmentally friendly and efficient compared to traditional organic solvents. Additionally, this research seeks to evaluate the antioxidant properties of the extracted fucoxanthin, further highlighting its potential applications in various industries. Methodology: In this study, deep eutectic solvents (DESs) including choline chloride: ethylene glycol, choline chloride: lactic acid, and choline chloride: acetic acid were employed for the extraction of fucoxanthin from brown algae. High-performance liquid chromatography (HPLC) was used for the identification of the extracted fucoxanthin, while its concentration was quantified using a spectrophotometer. Furthermore, the antioxidant properties of fucoxanthin were evaluated through the DPPH assay. Conclusions: The use of deep eutectic solvents (DESs) as an alternative to traditional solvents in the extraction of fucoxanthin from brown algae offers significant improvements