In this study we tried to investigate the transcription factor binding sites in the promoter regions of camel CSN1S1 gene and compared them with those located in domestic animal. After obtaining the promoter region sequence from NCBI database, identifying transcription binding site was done with PROMO online software, and their results were assessed for similarities and differences by using Excel and Visual Basic softwares. The results showed that the promoter region of the CSN1S1 gene have various types of binding sites for transcription factors. Although, a lot of common binding sites was observed between species, but some special binding sites were observed in camel. Overall, the present results show that the transcription conditions of this gene are often similar between species, but in special conditions are different from one species to another species.