10 فروردین 1403
امير وزيري زاده

امیر وزیری زاده

مرتبه علمی: استادیار
نشانی: پژوهشکده خلیج فارس - گروه شیلات و زیست شناسی دریا
تحصیلات: دکترای تخصصی / بیوشیمی
تلفن: 09177701465
دانشکده: پژوهشکده خلیج فارس

مشخصات پژوهش

عنوان Molecular Mass Homology between Proteins in Different Jellyfish Crude Venoms: A Systematic Review
نوع پژوهش مقالات در نشریات
کلیدواژه‌ها
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مجله TRANSYLVANIAN REVIEW
شناسه DOI
پژوهشگران ایرج نبی پور (نفر اول) ، غلامحسین محبی (نفر دوم) ، حسین وطن پور (نفر سوم) ، امیر وزیری زاده (نفر چهارم) ، امین استوار (نفر پنجم) ، ابراهیم نجف آبادی (نفر ششم به بعد)

چکیده

In this study, the molecular weight homology amongst different jellyfish proteins attained from electrophoretical methods, along with their biological activities according to literatures was systematically reviewed. In different studies, the protein components of various jellyfish venom were separated by electrophoretical analysis. For our subjects, in current review, the terms of “jellyfish toxins andSDS-PAGE” and “jellyfish toxins and electrophoresis methods” were searched in PubMed in 09/03/2015. From carefully chosen papers, a classification to nine groups (0-10,11-20, 21-40, 41-60, 61-80, 81-100, 101-140, 141-200 and 200 kDa) were regulated based on MW of bands. Then the approximate MW for each study was placed in their related groups. Results revealed the significant differences in presence and intensity of bands, numbers and size of venom compositions in different jellyfish. Though, there was some matching in presence of several fractions in venoms. The most dominant protein fraction in 39.02% of samples was occurred at approximate MW of 45 kDa. Then, both 30 and 40 kDa fractions with the same percentage of 34.15 %, and subsequently both 37 and 60 kDa, with equally percentage of 29.27 % were respectively presented in considered studies. Some of fractions were contribute to the toxic and lethal activities of jellyfish venoms. The jellyfish venom and their fractions contained protein or peptides with particular biological activities that might be responsible for some toxic effects of the venom on humans and animals. Identifying the molecular nature of these toxins is helpful to predict their biological activities.