Dara Bagheri

The increase in populating, the demand for aquaculture and the limitation of water resources have caused compressed breeding in the aquaculture industry, which is directly related to the spread of the disease and the use of antibiotics for treatment. Considering the side effects of antibiotics, the use of immune stimulants that increases resistance to environmental stresses and infectious diseases is very important in this industry. The present study was conducted with the aim of investigating the effect of beta -glucan on some growth and immunity parameters on Asian sea bass. For this purpose, 25g Asian sea bass were examined in three treatment s (with two rep l ications). The first treatment was fed only with basic diet prepared by Faradane h company (control) . The second treatment was fed with basic diet and 250 microliters of injectable glucan, (twice during the breeding period) (treatment 1) and the third group was fed with basic diet with oral prebiotic containing 15% beta-glucan (with final concentration of 1mg/g beta-glucan) (treatment 2). The use of prebiotic supplement containing beta -glucan (treatment 2) had a positive and significant effect on growth performance and immune factors of fish (P<0.05). Indicating its capability to induce non - specific immune defense in the fish. Treatment 2 showed the best results in terms of final weight (82.43g), specific growth rate (1.96%/day), weight gain percentage (224.55%), lysosome activity (39.5µg/mL), complement activity (128.8µg/mL), total immunoglobulin (16.55mg/mL) and immunoglobulin M (4.96mg/mL ) (P<0.05). As a result, the use of oral prebiotic supplement containing beta -glucan in sea bass diet is recommended due to its positive effects on physiological parameters and improvement of this species immunity.