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Abstract
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Multiple sclerosis is a disease of the central nervous system that cause major
psychological challenging in the patient all over the world. In this case, psychological
interventions can be useful this study was aimed to predictor factors of adherence to
treatment in patient with multiple sclerosis. This was on descriptive study with
questionnaire. One hundred – twenty patients were selected through accessible
sampling method from MS society of Tehran. They completed all administered
demographic questionnaire , Multiple Sclerosis Treatment Adherence Questionnaire
(MSTAQ) , General Self efficacy (GSE) , NEO five factor inventory (NEO-FFI) , Beck
Depression Inventory (BDI) , Short Form health survey questionnaire (SF-36) , Kattle
Anxiety Inventory (KAI) , Positive And Negative Affect Scales (PANAS) , Philips
Social Support Questionnaire (SSQ) and Feedback . Data was analyzed using
MONOVA repeated measure design , descriminent analysis and logistic regression .
The finding of this study indicated that there is a significant difference in adherence in
Multiple Sclerosis with depression , neuroticism , entroversion , conscientiousness ,
quality of life , family social support and anxiety (a=0/05) . The Results show that
adherence has direct relationship with psychological factors . Better treatment for this
patient in addition to medication should also be psychological counseling. This method
can reduce anxiety and depression and increase self efficacy and improve quality of
life
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